Molecular Epidemiology of Streptococcus Agalactiae
نویسنده
چکیده
1. Abstract 2. Introduction 3. Epidemiology of group B Streptococcus 3.1. Disease presentation and incidence 3.2. Asymptomatic colonization 3.3. Transmission and pathogenesis 3.4. Risk factors 4. Prevention efforts 5. Overview of molecular methods 6. Phenotypic characteristics 6.1. Serotype 6.2. Antibiotic susceptibility profiles 6.3. Expressed virulence factors 6.3.1. Polysaccharide capsule 6.3.2. Alpha and beta C proteins 6.3.3. Other cell surface proteins 6.4. Allelic variation at enzyme loci 7. Genotypic characteristics 7.1. Plasmids 7.2. Bacteriophage 7.3. Nucleotide sequences 7.3.1. Putative virulence genes 7.3.2. Mobile genetic elements 7.4. DNA fingerprinting 7.4.1. Restriction endonuclease analysis 7.4.2. Pulsed-field gel electrophoresis 7.4.3. Polymerase chain reaction (PCR)-based methods 8. Summary 9. Future work 10. Acknowledgment 11. References
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